Motorists face delays when temporary traffic restrictions are imposed on a busy road in the heart of the Hilltown.
Traffic lights and bans on turning will be in place on Hill Street between Bruce Street and Mortimer Street from Monday September 17.
The road will be closed to allow Scottish Water to carry out mains renewal work.
The improvements will be carried out by Caledonia Water Alliance as part of Scottish Water’s £5 million network upgrade across the city.
The upgrade, which started in 2016, was scheduled for completion in late 2017 but was delayed until spring this year and then again until late summer.
Ghulam Bajwa, who owns the Curryummy takeaway on Hilltown, said the roadworks will impact on his business.
He said: “Customers are put off by the roadworks – they have been going on for weeks.”
Lynne Short, convener of city development, said she understood residents’ frustration but that the works would be worth it in the end.
She said: “We continue to thank people for their patience and assure them that the work should be completed as soon as possible.
“We are having many miles of very old pipes replaced and in the end we will have a pipe network which is worthy of our city.”
A spokesman for Scottish Water said efforts are under way to ensure the renewal work is completed this autumn.
He said: “As the project has been rolled out across the city over the last couple of years the condition of some of the mains has meant parts of the work have had to be changed from lining, which is a quicker, less intrusive method of water mains renewal, to open cut work, which involves more extensive excavations.
“This has meant a significant change in timescale for some key parts of the project, which has impacted on the schedule for work as a whole. We appreciate the patience and understanding of customers and motorists in Dundee.”