There has been a 40% increase in the number of Tayside children admitted to hospital drunk since 2016.
Figures show a stark rise in children under the age of 16 being taken to accident and emergency.
Last year, a third of those youngsters taken to A&E were then kept in for further observation or treatment as hospital in-patients – a 50% rise on those requiring more than four hours treatment or observation than the year before.
In 2016, 30 children under the age of 16 were taken to A&E with alcohol intoxication, rising to 40 in 2017 and 42 by last month.
The NHS has a number of programmes to tackle the issue, which it runs in conjunction with other agencies in Tayside, including Dundee City Council and local police divisions.
A spokesman for NHS Tayside said: “There is a range of services and support available to children and young people in Tayside who run the risk of harmful exposure to alcohol and drugs.
“Services such as Key to Change in Dundee work with young people aged between 12 and 17.
“The focus of this service is concerned with risky behaviours in young people that may arise from alcohol or drug use. Services and supports are accessed through drop-ins, education sessions, one-to-one appointments, outreach and awareness-raising programmes.
“A number of programmes are offered, such as sexual health education, alcohol effects and dangers, information on the categories of drugs and effects, how to keep safe, as well as identifying emotions and feelings and healthy relationships.
“The Corner in Dundee also offers free, confidential support and drop-in services to young people aged between 11 and 19.”