Gillingham boss Steve Evans could resist the temptation to name an unchanged team for the fifth game in a row against Portsmouth.
Sunday’s win over Rochdale was the Gills’ seventh straight home victory but Evans conceded fatigue is beginning to play a part.
Substitutes Alex Jakubiak and Mark Marshall both lifted the hosts against Dale and could be rewarded with starting places.
Midfielder Mark Byrne remains a long-term absentee for the Gills with a season-ending knee injury.
Pompey boss Kenny Jackett will demand a reaction from his side after their away woes continued with a 3-1 defeat at MK Dons.
But various lingering injury concerns mean Jackett could be forced to name an unchanged side despite the quick turn-around.
Jackett is once again expected to be without Ryan Williams, who limped off in the opening stages of the Boxing Day win over Wycombe with a groin injury.
Ross McCrorie remains out due to a recurrence of his hamstring injury, while Lee Brown (Achilles) and Brandon Haunstrup (knee) are also sidelined.