Part of the A94 Forfar Road has been closed in both directions after a two-vehicle road traffic collision.
The road is closed and there is slow traffic in both directions between the A923 Blairgowrie Road junction and the Ardler turn-off junction, where police are directing traffic.
The incident was reported at 8.10 this morning and the first police unit arrived at the scene, near Easter Denhead farm, eight minutes later.
Six units are currently on the scene, dealing with injuries and attempting to get the road cleared.
A spokeswoman for Police Scotland Tayside Division said: “We believe there are injuries, but we don’t know the extent of them at this time.
“We are still dealing with it.”