Police say there are no obvious links between the three males and two females who died in December. Their ages ranged from 20 to 42.

Tayside Police drugs co-ordinator Inspector Wendy Symington said there was no single apparent cause for the increase in suspected drugs deaths.

“It is difficult to pinpoint a reason why drugs deaths are occurring, but it could be that the person’s tolerance is less than they thought, the strength and purity of the drug may be high, or an unknown mixing agent might be used which may cause an adverse reaction,” she said.

“Police have also had a number of drug seizures in high-profile operations recently, which has reduced availability across the region. Unfortunately, this means people may resort to sourcing what may not be their drug of choice.

“It is concerning that the number of suspected drugs deaths has increased, but we are working very closely with partner agencies in an effort to find a solution to the overdose and drugs death problem.”

In May, the Health Advisory Forum agreed a Tayside-wide approach to the issue was required.

“The Tayside Drug-Related Deaths Working Group was formed, bringing together the three Drug and Alcohol Action Teams (DAATs) and other partners to collate comprehensive information on drug death incidents and to develop strategic and operational responses to the problem of drug deaths,” Inspector Symington said.

She said the number of overdose cases was worrying, and said the help of friends and family was vital if police were to respond in time to assist victims.

“Unfortunately, every drug-related death represents a tragic waste of life and brings terrible grief to the families involved. It is important that the police and other agencies constantly work together to reduce the numbers of deaths,” she said.

“However, we can’t do all the work ourselves and it is really important that people are aware of what they should do in an emergency if their friends or family members are involved.

“You must give them the best chance to survive and it is essential that 999 is dialled at the earliest opportunity. Explain what has happened and take advice from the operator. If the person is unconscious, put them in the recovery position.”

Inspector Symington said the number of non-fatal overdoses in Dundee was also concerning.

“People have to understand that if illegal, controlled or prescription drugs are taken, sometimes for the reasons mentioned before or in excessive amounts, there is a real possibility of suffering an overdose,” she said.

“Some people are fortunate that they have been given the appropriate treatment in time, but others are not so lucky.

“It is important that the misery of drug addiction is tackled by reducing the demand for illicit drugs as well as targeting those concerned in the supply.

“By engaging and educating children, hopefully they can be given the information they need to resist peer pressure and see the benefits of a healthy lifestyle.”